bilimselkonular science
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A new study reveals that a previously undiscovered mouse gene reduces the two major pathological perturbations commonly associated with Alzheimer`s disease (AD). The research, published in the November 12 issue of the journal Neuron, finds that the novel gene interacts with a key cellular enzyme previously linked with AD pathology, thereby uncovering a new strategy [...]
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In this week`s Nature, Genome Institute of Singapore (GIS) scientists report a technological advance in the study of gene expression and regulation in the genome`s three-dimensional folding and looping state through the development of a novel technology.
The technology is ChIA-PET (Chromatin Interaction Analysis using Paired End Tag sequencing). Chromatin is a complex combination of DNA [...]
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A novel method of detection of cervical cancer cells has been developed by Clarkson University Professor Igor Sokolov`s group, an affiliate of the University`s Nanoengineering and Biotechnology Laboratories Center (NABLAB).
The group`s paper is published in Small.
Methods for detection of cancer cells are mostly based on traditional techniques used in biology, such as visual identification of [...]
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Tamoxifen may worsen breast cancer in a small subset of patients. Research published in BioMed Central`s open access journal Breast Cancer Research suggests that in patients who show reduced or absent expression of the protein E-cadherin, commonly used anti-oestrogen drugs such as tamoxifen may promote more harmful cancer cell behaviour.
A team of researchers co-ordinated by [...]
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Interleukin-12 is a naturally occurring protein essential for the proper functioning of the human immune system. Having either too much or too little interleukin-12 may play a role in the development of many diseases, including some cancers and auto-immune disorders like Crohn`s, psoriasis, and rheumatoid arthritis. In turn, modulating interleukin-12 levels could yield new therapies [...]
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Stem cells derived from bone marrow may serve as a novel therapeutic option to treat a disease called epidermolysis bullosa (EB), a disorder characterized by extraordinarily fragile skin, according to a study prepublished online in Blood.
Epidermolysis bullosa is a disorder characterized by extraordinarily fragile skin and blistering on touch, akin [...]
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Moderate alcohol intake is associated with higher levels of omega-3 fatty acids in plasma and red blood cells. This is the major finding of the European study IMMIDIET that will be published in the January issue of the American Journal of Clinical Nutrition.
The study suggests that wine does better than other alcoholic drinks. This effect [...]
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Long thought of as mere bystanders, astrocytes are crucial for the survival and well-being of motor neurons, which control voluntary muscle movements. In fact, defective astrocytes can lay waste to motor neurons and are the main suspects in the muscle-wasting disease amyotrophic lateral sclerosis (ALS).
To get to the root of this complicated relationship, researchers from [...]
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Researchers at the Texas A&M Health Science Center Institute of Biosciences and Technology, and the University of Edinburgh have uncovered how a bacterial pathogen interacts with the blood coagulation protein fibrinogen to cause methicillin-resistant Staphylococcus aureus (MRSA) infections, a finding that could aid in developing therapeutics against the potentially deadly disease.
Once occurring more commonly in [...]
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