bilimselkonular science
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A comprehensive mouse model of inherited prion disease exhibits cognitive, motor, and neurophysiological deficits that bear a striking resemblance to the symptoms experienced by patients with the human version of "mad cow disease," Creutzfeldt-Jakob disease (CJD). The research, published by Cell Press in the November 26th issue of the journal Neuron, provides exciting insight into [...]
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A study released by researchers at the Columbia Center for Children`s Environmental Health (CCCEH) at Columbia University`s Mailman School of Public Health shows that developing antibodies to cockroach and mouse proteins is associated with a greater risk for wheeze, hay fever, and eczema in preschool urban children as young as three years of age.
The study, [...]
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For the first time researchers have shown that a commonly used anesthetic can produce changes associated with Alzheimer`s disease in the brains of living mammals, confirming previous laboratory studies.
In their Annals of Neurology report, which has received early online release, a team of Massachusetts General Hospital (MGH) investigators shows how administration of the gas isoflurane [...]
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A new study highlights the role of a charge-switching enzyme in nervous system deficits characteristic of multiple sclerosis and other related neurological illness.
Multiple sclerosis (MS) is one of several diseases in which myelin – the insulator for electrical signaling in the nervous system – breaks down and causes severe deficits in brain and nerve function. [...]
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Discussion of a man`s background, attitude, and sexual history isn`t just the fodder of Sex and The City episodes – in the future, it could also be a way of evaluating his risk of diabetes.
Risk of developing type 2 diabetes and metabolic syndrome is determined by an individual`s genetic background. Since this background has [...]
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Researchers have defined a mutation in the mouse genome that mimics progressive hearing loss in humans. A team from the Wellcome Trust Sanger Institute in Cambridge, UK, working with colleagues in Munich and Padua, found that mice carrying a mutation called Oblivion displayed problems with the function of hair cells in the inner ear, occurring [...]
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Researchers of the Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital used the novel inhibitor AZD2281 to target breast cancer, in which the BRCA1-gene plays a role, in a genetically engineered mouse model. Treatment resulted in tumor regression and a strong increase in survival without signs of toxicity. The inhibitor, which recently entered trials in [...]
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