bilimselkonular science
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A new study reveals that a previously undiscovered mouse gene reduces the two major pathological perturbations commonly associated with Alzheimer`s disease (AD). The research, published in the November 12 issue of the journal Neuron, finds that the novel gene interacts with a key cellular enzyme previously linked with AD pathology, thereby uncovering a new strategy [...]
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Becoming "hard of hearing" is a standard but unfortunate part of aging: A syndrome called age-related hearing loss affects about 40 percent of people over 65 in the United States, and will afflict an estimated 28 million Americans by 2030.
"Age-related hearing loss is a very common symptom of aging in humans, and also is universal [...]
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What do you get when you cross a mouse with poor hearing and a mouse with even worse hearing? Ironically, a new strain of mice with "golden ears" — mice that have outstanding hearing as they age.
The work by one of the world`s foremost groups in age-related hearing loss, or presbycusis, marks the first time [...]
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Over a period of five years, scientists at the Johannes Gutenberg University Mainz have managed to create a genetically modified mouse in which the activity of the blood stem cells can be tracked. "This mouse was created from a single embryonic stem cell.
We are able to observe its blood stem cells in detail and see [...]
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A large proteomics study on the brains of newborn mice provides more evidence that numbing drugs often used in obstetric or pediatric medicine can have profound and long-term negative effects, even after minimal exposure.
This study highlights the delicate state of the developing nervous system and reinforces the use of caution when administering sedatives, anesthetics, and [...]
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There are many ways to die, but amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig`s disease must be one of the worst. By the time a patient notices muscle weakness, the neurons that control the muscles have already begun dying, in an untreatable process that brings death within two to five years.
In a series [...]
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A breakthrough technique that allows scientists to view individually-labeled tumor cells as they move about in real time in a live mouse may enable scientists to develop microenvironment-specific drugs against cancer, researchers report at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.
With this technique, researchers at the [...]
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A worldwide group of scientists has created an infectious prion disease in a mouse model, in a step that may help unravel the mystery of this progressive disease that affects the nervous system in humans and animals. The research team, including Christina J. Sigurdson, D.V.M., Ph.D., assistant professor of pathology at the University of [...]
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Scientists have successfully created the first induced pluripotent stem (iPS) cell lines from adult monkey skin cells. The research, published by Cell Press in the December issue of the journal Cell Stem Cell, demonstrates that the method of direct reprogramming is conserved among species and may be useful for creation of clinically valuable primate models [...]
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Some 80,000 people in Germany suffer from multiple sclerosis – their immune system attacks and destroys healthy nerve tissue. Researchers at the Heidelberg University Hospital and the German Cancer Research Center in Heidelberg have succeeded in vaccinating mice with specially treated, autologous immune cells and preventing them from developing encephalitis, which is similar to multiple [...]
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