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A study appearing in Science Translational Medicine puts scientists one step closer to clinical trials to test a gene delivery strategy to improve muscle mass and function in patients with certain degenerative muscle disorders.
Severe weakness of the quadriceps is a defining feature of several neuromuscular disorders. Researchers at Nationwide Children`s Hospital have shown that a [...]

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The war between the sexes has been fought on many fronts throughout time — from humans to birds to insects, the animal kingdom is replete with species involved in their own skirmishes. A recent study by Dr. Sarah Eppley and colleagues at Portland State University published in the November issue of the American Journal of [...]

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Among postmenopausal women, the risk of hip fractures increases steeply with age and is seven times higher in 70-year-olds than in 50-year-olds, according to a study in this week`s PLoS Medicine.
The study also found that in women aged 50-54 years (i.e. around the time of menopause), although hip fractures are rare, the risk of a [...]

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If taking nonsteroidal antiinflammatory drugs (NSAIDs) such as ibuprofen or naproxen is to protect you from developing Alzheimer disease then you will have to start taking them at a very early age according to research in a mouse model of the disease.
Emerging data indicate that an early molecular event in the development of Alzheimer disease [...]

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Human movement is a key factor of dengue virus inflow in Rio de Janeiro, according to results from researchers based at the Oswaldo Cruz Foundation (Fiocruz) in Brazil. The results, based on data from a severe epidemic in 2007-2008, contribute to new understanding on the dynamics of dengue fever in the second largest city in [...]

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Becoming "hard of hearing" is a standard but unfortunate part of aging: A syndrome called age-related hearing loss affects about 40 percent of people over 65 in the United States, and will afflict an estimated 28 million Americans by 2030.
"Age-related hearing loss is a very common symptom of aging in humans, and also is universal [...]

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Operators of subsea fields on the continental shelf spend vast amounts of money on keeping harmful ice-like crystals under control. SINTEF scientists are now looking for a cheaper solution to the problem.
The researchers are trying to solve the mystery of what happens when hydrates are formed. These ice-like crystals can accumulate in the pipelines that [...]

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High blood pressure, evidence of arterial disease and markers of inflammation in the blood in middle age appear more common in individuals whose parents have Alzheimer`s disease than in individuals without a parental history of the condition, according to a report in the November issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Previous [...]

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The impact of airborne nitrogen released from the burning of fossil fuels and wide-spread use of fertilizers in agriculture is much greater that previously recognized and even extends to remote alpine lakes, according to a study published Nov. 6 in the journal Science.
Examining nitrogen deposition in alpine and subalpine lakes in Colorado, Sweden and Norway, [...]

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Weak Link In Cancer Cell Armor Identified

by mokosam on November 14, 2009

The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves. Researchers at the Cornell University College of Veterinary Medicine have discovered that inactivation of a DNA repair gene called Hus1 efficiently kills cells lacking p53 — a gene mutated [...]

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