bilimselkonular science
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University of Rochester Medical Center scientists discovered a gene mutation that impairs the placenta and also is influential in cancer development, according to a new study.
The investigation is the first to link the key placental gene, SENP2, to the well-known p53 protein, which is defective in 50 percent of all cancers.
Until now, the SENP2 gene`s [...]
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Rather than testing for individual marker genes or proteins, researchers at the University of California, San Diego (UC San Diego) and the Moores UCSD Cancer Center have evidence that groups, or networks, of interactive genes may be more reliable in determining the likelihood that a form of leukemia is fast-moving or slow-growing.
One of the problems [...]
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Researchers from Virginia Commonwealth University have identified a new anti-tumor gene called SARI that can interact with and suppress a key protein that is overexpressed in 90 percent of human cancers. The discovery could one day lead to an effective gene therapy for cancer.
According to Paul B. Fisher, M.Ph., Ph.D., professor and chair of the [...]
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One of the fastest translations of a basic research discovery into a promising clinical trial for an "untreatable" and fatal disorder will be discussed publicly for the first time by the key players in this remarkable research story, on Dec. 14, at the American Society for Cell Biology (ASCB)`s annual meeting in San Francisco.
The disease [...]
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Researchers at the University of Maryland School of Medicine in Baltimore have discovered a novel gene mutation among the Old Order Amish population that significantly reduces the level of triglycerides in the blood and appears to help prevent cardiovascular disease.
"We found that about 5 percent of the Amish have a gene mutation that speeds up [...]
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An international research team has identified 11 novel locations in the human genome where common variations appear to influence cholesterol or triglyceride levels, bringing the total number of lipid-associated genes to 30. While major mutations in some of these genes have been known to underlie rare lipid metabolism disorders, it is becoming apparent that [...]
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Scientists at the University of Michigan have shown that gene therapy can be used to successfully stop the development of periodontal disease, the leading cause of tooth loss in adults.
Using gene transfer to treat life threatening conditions is not new, but the U-M group is the first known to use the gene delivery approach to [...]
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A University of British Columbia geneticist has discovered a gene mutation that can cause the most common eye cancer – uveal melanoma.
Catherine Van Raamsdonk, an assistant professor of medical genetics in the UBC Faculty of Medicine and a team of researchers, have discovered a genetic mutation in a gene called GNAQ that could be responsible [...]
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To decipher how cancer develops, Johns Hopkins Kimmel Cancer Center investigators say researchers must take a closer look at the packaging.
Specifically, their findings in the December 2, 2008, issue of PLoS Biology point to the three dimensional chromatin packaging around genes formed by tight, rosette-like loops of Polycomb group proteins (PcG). The chromatin packaging, a [...]
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In the race for bioengineered crops, sequencing the genome could be considered the first leg in a multi-leg relay. Once the sequence is complete, the baton is passed forward to researchers to identify genes’ functions. A draft sequence of the soybean genome is now available, and the complete genome will be available soon.
Taking the next [...]
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