bilimselkonular science
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CSIRO scientists have developed a new system to screen for compounds that can inhibit one of the processes that takes place during the progression of Alzheimer’s disease. Certain yeast species could be used to develop this rapid screening process. Folate has been shown to be beneficial in the screening system.
Lead author, CSIRO’s Dr Ian Macreadie [...]
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Oregon Health & Science University Knight Cancer Institute researchers are closer to understanding why certain chronic myeloid leukemia mutations are not stopped by the revolutionary targeted cancer pill, Gleevec, or similar therapies in that drug family.
The research was presented Dec. 8, at the 50th Annual American Society of Hematology conference in San Francisco.
Gleevec, also called [...]
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In the treatment of pain, inflammation and fever, non-steroid anti-rheumatic drugs (NSAR) such as acetylsalicylic acid – more commonly known as Aspirin – or Ibuprofen have always been popular choices. However, had they been tested using today`s stringent criteria, many of these drugs would not have passed the clinical trial stage, due to the potential [...]
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Infectious disease experts warn that new drugs are urgently needed to treat six drug-resistant bacteria that cause most hospital infections and increasingly escape the effects of antibiotics.
The ESKAPE pathogens—as these six bad bugs have been dubbed—are still on the loose more than four years after the Infectious Diseases Society of America (IDSA) first drew attention [...]
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Antibiotics are the single largest class of agents that cause idiosyncratic drug-induced liver injury (DILI), reports a new study in Gastroenterology, an official journal of the American Gastroenterological Association (AGA) Institute. DILI is the most common cause of death from acute liver failure and accounts for approximately 13 percent of cases of acute liver failure [...]
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Osteoporosis is a growing concern among breast cancer survivors and their doctors, because certain cancer drugs can cause bone loss.
But a new study has found that cancer drugs aren`t the only culprits. Among 64 breast cancer patients referred to a bone health clinic, 78 percent had at least one other cause of bone loss, [...]
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Once hailed as a miracle weight-loss drug, Fen-phen was removed from the market more than a decade ago for inducing life-threatening side effects, including heart valve lesions. Scientists at UT Southwestern Medical Center are trying to understand how Fen-phen behaves in the brain in order to develop safer anti-obesity drugs with fewer side effects.
In a [...]
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A team of cancer researchers from several Boston academic medical centers has discovered a potential treatment for a group of tumors that have resisted previous targeted therapy approaches. In their Nature Medicine report, which is receiving early online release, investigators from Dana-Farber Cancer Institute (DFCI), Massachusetts General Hospital (MGH) Cancer Center, and Beth Israel [...]
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