bilimselkonular science
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Dr. Fred H. Gage (The Salk Institute for Biological Studies) and colleagues reveal a role for the Hippo signaling pathway in the regulation of vertebrate neural development, identifying new factors – and potential therapeutic targets – that may be involved in congenital brain size disorders and neurological tumor formation.
Establishing the basic embryonic brain requires the [...]
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A study released by researchers at the Columbia Center for Children`s Environmental Health (CCCEH) at Columbia University`s Mailman School of Public Health shows that developing antibodies to cockroach and mouse proteins is associated with a greater risk for wheeze, hay fever, and eczema in preschool urban children as young as three years of age.
The study, [...]
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A gene essential to the growth and development of most organ systems in the body also is vital to female – but not male – embryonic sexual development, scientists report this month.
The study, from researchers at the University of Illinois and the University of Texas, appears in Human Molecular Genetics. The findings lend support to [...]
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Like skilled assassins, many diseases seem to know exactly what types of cells to attack. While decimating one cadre of cells, diseases will inexplicably spare a seemingly identical group of neighbors. What makes cells vulnerable or not depends largely on the kinds and amounts of proteins they produce – their "translational profile," in the [...]
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Discovery of the most intact female pelvis of Homo erectus may cause scientists to reevaluate how early humans evolved to successfully birth larger-brained babies.
"This is the most complete female Homo erectus pelvis ever found from this time period," said Indiana University Bloomington paleoanthropologist Sileshi Semaw. "This discovery gives us more accurate information about the Homo [...]
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Stem cells don’t just become a part of the liver or the brain in a flash; it takes a complex molecular choreography and requires that specific genes be switched on and off at specific times. Some of these genes are regulated through a process by which proteins in the cell nucleus, called histones, are chemically [...]
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Researchers at the University of Southern California (USC) have identified a novel mechanism in the regulation and differentiation of neural stem cells.
Researchers found that the protein receptor Ryk has a key role in the differentiation of neural stem cells, and demonstrated a signaling mechanism that regulates neuronal differentiation as stem cells begin to grow into [...]
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Scientists at the University of Liverpool have developed a new technology which can dramatically improve the effectiveness of antibacterial treatments.
Drugs with the ability to dissolve have much stronger efficacy, however many drugs are insoluble. In order to compensate, drugs often need to be administered in higher doses. This increases the possibility of bacteria and other [...]
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MIT biologists have discovered that the organization of DNA`s packing material plays a critical role in directing stem cells to become different types of adult cells.
The work, to be published in the journal Cell on Nov. 14, could also shed light on the possible role of DNA packaging in cancer development.
Led by Laurie Boyer, assistant [...]
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Every day 2000 children die from malaria in Africa alone. The infection is transmitted from human to human by biting mosquitoes and remains one of the world’s most devastating diseases. Despite many years of effort a vaccine is still not available but is urgently needed, if we are to make an impact on this enormous [...]
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