Posts tagged as:

Development

It`s no bigger than a stamp packet but it has the potential to allow rapid development of a new generation of drugs and genetic engineering organisms, and to better control in-vitro fertilization.
Engineering researchers at McMaster University have fabricated a palm-sized, automated, micro-injector that can insert proteins, DNA and other biomolecules into individual cells at volumes [...]

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Mobile phones are on the verge of becoming powerful tools to collect data on many issues, ranging from global health to the environment.
Computer scientists at the University of Washington have used Android, the open-source mobile operating system championed by Google, to turn a cell phone into a versatile data-collection device. Organizations that want a fully [...]

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Researchers at the California Institute of Technology (Caltech) have shown that a highly specific intrabody (an antibody fragment that works against a target inside a cell) is capable of stalling the development of Huntington`s disease in a variety of mouse models.
"Gene therapy in these models successfully attenuated the symptoms of Huntington`s disease and increased life [...]

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Using novel imaging, labeling, and data-analysis techniques, scientists from the California Institute of Technology (Caltech) have been able to visualize, for the first time, large numbers of cells moving en masse during some of the earliest stages of embryonic development.
The findings not only provide insight into this stage of development–called gastrulation–but give a more general [...]

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Finnish scientists have reported a breakthrough in understanding the development of type 1 diabetes. They discovered disturbances in lipid and amino acid metabolism in children who later progressed to type 1 diabetes, also known as juvenile diabetes. The alterations preceded the autoimmune response by months to years. The study may prompt [...]

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No matter the species, from flies to humans, we all start the same: a single-cell fertilized egg that embarks on an incredible journey.  The specifics of this journey are being uncovered at Rutgers University-Camden, where a biologist is researching how from one cell a jumble of many are able to organize and communicate, allowing life [...]

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RNA Interference Can Facilitate Vaccine Development

by mokosam on December 13, 2008

Pharmaceutical companies and universities are racing to develop drugs that use the gene silencing mechanism known as RNA interference to treat a host of diseases. Now, a new study opens up an entirely new possibility for this powerful tool: Researchers at the University of Georgia have demonstrated for the first time that RNA interference can [...]

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Gene Packaging Tells Story Of Cancer Development

by mokosam on December 13, 2008

To decipher how cancer develops, Johns Hopkins Kimmel Cancer Center investigators say researchers must take a closer look at the packaging.
Specifically, their findings in the December 2, 2008, issue of PLoS Biology point to the three dimensional chromatin packaging around genes formed by tight, rosette-like loops of Polycomb group proteins (PcG). The chromatin packaging, a [...]

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A UCSF study has found that a surprisingly high number of maternal cells enters the fetus during pregnancy, prompting the generation of special immune cells in the fetus that suppress a response against the mother.
Such peaceful co-existence represents a form of "tolerance," or the way in which the immune system of one individual is able [...]

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Children and teenagers with even mild cases of anorexia exhibit abnormal bone structure, according to a new study appearing in the December issue of Radiology and presented at the annual meeting of the Radiological Society of North America (RSNA).
"Adolescence is the most critical period for growth of bone mass, and the onset of anorexia interferes [...]

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